About 2 results found for searched term "FR901464" (0.185 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M13347 | FR901464 | Others |
| FR901464 is an effective spliceosome inhibitor with significant antitumor and anticancer effects. | ||
| M30035 | Spliceostatin A | Others |
| Spliceostatin A, the FR901464 methylated derivative, is a potent anti-tumor agent. Spliceostatin A inhibits splicing and promotes pre-mRNA accumulation by binding SF3B1. SF3B1 is a subcomplex of U2 small nuclear ribonucleoprotein in the spliceosome. Spliceostatin A induces Apoptosis in chronic lymphocytic leukemia (CLL) cells. | ||
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